Skip to content

Debate over organ donation systems: which approach, consent-based or presumed consent, is more effective?

Organ Donation Methodology: Which 'Opt-In' or 'Opt-Out' Approach is More Effective?

Every 10 minutes in the United States, a new individual is placed on the organ transplant waitlist.
Every 10 minutes in the United States, a new individual is placed on the organ transplant waitlist.

Organ donation policies vary widely across the globe. A Korean research team, spearheaded by Prof. Eamonn Ferguson from the University of Nottingham, UK, delved into the organ donation practices of 48 nations to decipher which method is more effective.

In opt-in systems, individuals must actively register to donate their organs posthumously. In contrast, opt-out systems assume consent for organ donation unless a specific request to opt-out is made before death. However, inaction can create complications.

For instance, an opt-in system might result in individuals who would've desired to donate not doing so (a false negative). On the flip side, an opt-out system could lead to an individual who doesn't wish to donate becoming a donor (a false positive).

The US asserts an opt-in system, with over 28,000 transplants accomplished last year due to organ donors, yet 18 individuals still die daily due to insufficient donated organs.

An exploration by the University of Nottingham, University of Stirling, and Northumbria University, UK, over a 13-year period revealed intriguing findings. Countries employing opt-out systems proved to have a higher total number of kidneys donated, the organ people often desperately wait for on transplant lists. Moreover, these systems registered a greater overall number of organ transplants.

However, opt-in systems exhibited a higher rate of living donor kidney donations. This subtleness, the influence of policy on living donation rates, as stated by Prof. Ferguson, is noteworthy and offers interesting insights.

The authors acknowledge that their study had limitations, such as not differentiating varying degrees of opt-out legislation or factoring other factors that could influence organ donation.

Prof. Ferguson proffers future studies focusing on the perspectives and attitudes of individuals faced with the decision to opt-in or opt-out, complemented by institutional or societal elements. By combining these approaches, researchers may uncover more about the impact of consent legislation on organ donation and transplantation rates.

In conclusion, countries that follow opt-out consent have higher total deceased organ donation rates but lower living donor rates, as well as higher totals of livers and kidneys transplanted. Yet, they still face organ donor shortages. The researchers emphasize that shifting the system may not single-handedly resolve such issues. Instead, refining consent legislation or adopting aspects of the "Spanish Model," which boasts a world-leading organ donation rate, may enhance donor rates.

The debate on whether farming animal organs for human transplants could address the organ shortage persists. Future studies could shed light on this intriguing topic.

  1. The study by the research team, including Prof. Eamonn Ferguson from the University of Nottingham, revealed that countries with opt-out systems for organ donation had a higher total number of kidneys donated and a greater overall number of organ transplants.
  2. In contrast, opt-in systems showed a higher rate of living donor kidney donations, suggesting that the influence of policy on living donation rates is a significant, noteworthy aspect.
  3. The researchers suggested that future studies should focus on understanding the perspectives and attitudes of individuals deciding to opt-in or opt-out, as well as institutional and societal factors, to gain more insights into the impact of consent legislation on organ donation and transplantation rates.
  4. The debate continues about whether farming animal organs for human transplants could potentially address the organ shortage, with future studies expected to contribute valuable insights on this fascinating topic.

Read also:

    Latest