Genetic Link Found in 9.5% of Young Sudden Deaths
Researchers have discovered a significant genetic link in sudden deaths among young people. The MOSCAT Project found that 9.5% of sudden deaths in individuals under 35 have a hereditary cardiac cause. This discovery opens doors for preventive measures and early detection in relatives.
The study, conducted by the Clinic for Human Genetics at the University Medical Center Hamburg-Eppendorf (UKE) under the leadership of Dr. Woitschach, analyzed over 1,200 cases of sudden deaths. Among those aged up to 35, 685 cases were examined. Genetic tests were suggested when autopsies failed to determine the cause of death or when there was suspicion of hereditary structural cardiopathy.
The highest genetic incidence was found in deaths from thoracic aortic aneurysms and myocarditis, at 33.3%. In the group aged between 36 and 50, the rate of sudden death associated with genetic causes was lower at 4.9%, with thoracic aortic aneurysms being the main cause. Routine genetic tests were recommended for the group of 685 people to detect changes in DNA associated with hereditary diseases or health risks.
The MOSCAT Project's findings highlight the importance of genetic testing in sudden cardiac death cases under 35. Early detection can lead to preventive measures and improved outcomes for relatives at risk. Further research is encouraged to better understand and address these genetic factors.
