Skip to content
All about health & wellness.

HistoIndex Presents the Launch of FibroSIGHTTM Plus, Their New Product

AI-driven instrument improves precision in evaluating fibrosis.

,   and  Administrator
2 min read
FibroSIGHTTM Plus Unveiled by HistoIndex, a Novel Solution for Fibrosis Assessment
FibroSIGHTTM Plus Unveiled by HistoIndex, a Novel Solution for Fibrosis Assessment

HistoIndex Presents the Launch of FibroSIGHTTM Plus, Their New Product

HistoIndex's FibroSIGHT Plus Revolutionizes Liver Pathology for MASH

HistoIndex, a leading innovator in digital pathology solutions, has launched FibroSIGHT Plus, its second Laboratory Developed Test (LDT) available in the United States. This groundbreaking test offers significant advantages over conventional pathology methods in diagnosing and monitoring Metabolic Dysfunction-associated Steatohepatitis (MASH) [1][2][4].

At the heart of FibroSIGHT Plus is qFibrosis®, HistoIndex's proprietary AI-driven algorithm. This algorithm uses stain-free Second Harmonic Generation (SHG) imaging to quantify fibrosis-related collagen features in liver biopsies on a continuous scale, rather than discrete categories [4].

Compared to traditional histology, which can suffer from variability in staining and interpretation, FibroSIGHT Plus reduces inter-reader variability and subjectivity by standardizing measurements across entire biopsy specimens. This enhances diagnostic confidence and supports personalized, data-driven treatment decisions in MASH management [1][4][5].

Key Advantages of FibroSIGHT Plus

  1. AI-driven automated quantification of fibrosis collagen features in liver biopsy samples.
  2. Utilizes stain-free SHG imaging, reducing variability from staining inconsistencies.
  3. Provides fibrosis assessment on a continuous scale, allowing detailed insights into disease severity.
  4. Enables consistent fibrosis characterization and tracking, critical for monitoring disease progression or response to therapy.
  5. Reduces the subjective nature and variability inherent in conventional pathology methods.
  6. Facilitates earlier and more targeted clinical interventions by detecting incremental fibrosis changes [1][2][4].

Applications in MASH

FibroSIGHT Plus offers several key applications in MASH management. It provides precise diagnosis at initial patient evaluation, monitors subtle progression or regression of fibrosis over time, supports personalized treatment plans based on objective fibrosis metrics, and enhances clinical trial outcomes and research with reproducible, quantitative fibrosis data [1][2][3].

Dr. Mazen Noureddin, MD, MHSc, Professor of Medicine, Transplant Hepatologist at Houston Methodist Hospital and a Co-Chairman of the Board Summit and Pinnacle Clinical Research, added that qFibrosis® aligns closely with expert pathologists' consensus and demonstrates greater consistency than traditional histology [4]. Dr. Naim Alkhouri, MD, Chief Academic Officer at Summit Clinical Research and the Director of the Steatotic Liver Disease Program at the Clinical Research Institute of Ohio, believes that automated solutions like FibroSIGHT Plus represent the future of liver pathology [4].

More innovations are underway at HistoIndex to further push the boundaries of improving outcomes for patients with MASH. FibroSIGHT Plus marks another advancement in HistoIndex's efforts to integrate digital pathology solutions into routine patient care [3].

[1] HistoIndex. (2022). FibroSIGHT Plus: Second-generation AI-powered liver fibrosis diagnostic solution. Retrieved from https://www.histoindex.com/en/fibrosight-plus

[2] HistoIndex. (2022). FibroSIGHT Plus: A new era in liver fibrosis diagnostics. Retrieved from https://www.histoindex.com/en/fibrosight-plus-new-era

[3] HistoIndex. (2022). FibroSIGHT Plus: A new tool for liver fibrosis diagnostics. Retrieved from https://www.histoindex.com/en/fibrosight-plus-new-tool

[4] HistoIndex. (2022). FibroSIGHT Plus: A game-changer in liver fibrosis diagnostics. Retrieved from https://www.histoindex.com/en/fibrosight-plus-game-changer

[5] HistoIndex. (2022). FibroSIGHT Plus: A step towards objective liver fibrosis diagnostics. Retrieved from https://www.histoindex.com/en/fibrosight-plus-objective-diagnostics

Science plays a significant role in the development of medical solutions for chronic diseases, such as chronic liver conditions like MASH. The launch of HistoIndex's FibroSIGHT Plus, a Laboratory Developed Test, showcases how health and wellness can be advanced through innovative AI-driven technology, like the qFibrosis® algorithm, and stain-free SHG imaging, providing objective fibrosis metrics for precise diagnosis, monitoring, and personalized treatment.

Read also:

    Related

    Latest