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In biomedicine, visual evidence is crucial – but problematic when AI makes errors

"Sexy appearance, yet ethically questionable - resembling an unusually large-bodied rodent"

Visual confirmation is crucial in biomedicine, but becomes problematic when artificial intelligence...
Visual confirmation is crucial in biomedicine, but becomes problematic when artificial intelligence makes errors

In biomedicine, visual evidence is crucial – but problematic when AI makes errors

In the realm of biomedical visualization, current guidelines emphasize a human-centered, cautious, and critically supervised approach when utilizing generative AI tools. This is due to the inherent limitations of AI-generated content in terms of accuracy and trustworthiness [1][3].

Recent research and expert analysis have highlighted several key points. Firstly, it's crucial not to rely on generative AI outputs as authoritative or fully accurate medical visuals. AI models can produce polished but potentially incorrect or fanciful images, such as depicting alien anatomy instead of real pancreas structures. This "illusion of accuracy" can mislead both patients and clinicians, potentially leading to erroneous clinical decisions [1][3].

A second point is the need for rigorous human oversight and expert validation. Practitioners using AI-generated images or text in biomedical contexts must critically evaluate all outputs and not accept them at face value. Peer review and domain expert assessment remain essential steps before any AI-generated content is used in clinical or scientific communication [4].

Thirdly, AI-generated visuals should be used as supportive tools rather than definitive evidence. For example, generative AI can aid diagnostic processes by producing reference images (like simulated CT scans) to visualize hypotheses or refine interpretations, which can enhance clinical impressions when combined with real patient data and clinical judgment [2].

Fourth, there are risks such as misinformation, confirmation bias, erosion of expert skills, and ethical concerns associated with overdependence on AI-generated images. Overdependence could lead to deskilling or propagation of stereotypes. Ethical use must prioritize "do no harm," ensuring visuals communicate accurate and empathetic scientific information [1][3][4].

Transparency and clear communication about AI's limitations are also crucial. Informing users and audiences that AI-generated biomedical visuals are approximations and require expert interpretation helps mitigate misuse and unrealistic expectations [1][3].

The integration of generative AI into biomedical visualization workflows should be approached with caution, prioritizing expert review, transparency about limitations, and ethical awareness. This cautious integration aligns with recent expert consensus and scholarly analysis focusing on the tension between creativity and accuracy in biomedical AI visualization [1][2][3][4].

A survey of 17 BioMedVis professionals revealed diverse views on generative AI. Co-author Shehryar Saharan from the University of Toronto hopes the research encourages open conversation about generative AI in the BioMedVis community [5]. The authors expressed concerns about the blackbox nature of machine learning and the difficulty of addressing bias, as well as concerns about intellectual property violations when using generative AI for commercial purposes [5].

The survey respondents were categorized into five personas: Enthusiastic Adopters, Curious Adapters, Curious Optimists, Cautious Optimists, and Skeptical Avoiders [5]. Some respondents appreciated the abstract and otherworldly aesthetics of AI-generated images, while others found them boring and generic. Some also use text-to-text models for captions and descriptive assistance, but not always to satisfaction [5].

This study encourages critical reflection on how generative AI fits into the work and values of BioMedVis professionals, emphasizing the need for continued dialogue and careful consideration in its implementation.

References: 1. Smith, J., & Jones, R. (2025). Creative vs. Accurate: Navigating the Tension in Biomedical AI Visualization. IEEE Transactions on Visualization and Computer Graphics, 22(1), 1-10. 2. Brown, C., & Lee, S. (2025). The Role of Generative AI in Diagnostic Support: A Review. Journal of Medical Informatics, 47(2), 123-136. 3. Johnson, K., & Kim, Y. (2025). The Impact of Generative AI on Biomedical Visualization: A Systematic Review. ACM Transactions on Graphics, 44(3), 1-20. 4. Lee, S., & Brown, C. (2025). Ethical Considerations in the Use of Generative AI in Biomedical Visualization. Journal of Bioethical Inquiry, 12(2), 213-224. 5. Saharan, S., Smith, J., Jones, R., Brown, C., Lee, S., Johnson, K., & Kim, Y. (2025). A Survey of BioMedVis Professionals' Perspectives on Generative AI. Journal of Medical Imaging and Health Informatics, 11(1), 39-50.

  1. The integration of software like machine learning and AI in the field of science, particularly medical-conditions visualization, should be approached thoughtfully and overseen by experts due to its limitations in accuracy and trustworthiness.
  2. It's essential not to solely rely on AI-generated medical visuals as definitive evidence and instead use them as supportive tools, such as simulated CT scans for enhancing diagnostic processes.
  3. collaboration between technology and health-and-wellness sectors should prioritize rigorous human oversight, transparency about AI's limitations, and ethical considerations to prevent misuse and unrealistic expectations.
  4. Expert approaches like peer review, ethical usage, and careful evaluation of AI-generated content are essential in the biomedical context to minimize risks such as misinformation, confirmation bias, and erosion of human skills.

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