Interactions of Viibryd: Information on other drugs, alcohol, and related substances
Viibryd, a brand-name prescription drug used to treat major depressive disorder, can interact with a variety of substances, including certain medications, alcohol, and some supplements. It's crucial to be aware of these potential interactions to ensure safe and effective treatment.
Viibryd can interact with a range of drugs, such as monoamine oxidase inhibitors (MAOIs), blood thinners, antiplatelets, amphetamines, benzodiazepines, triptans, serotonin-norepinephrine reuptake inhibitors, selective serotonin reuptake inhibitors, nonsteroidal anti-inflammatory drugs, certain antifungal drugs, certain antiseizure drugs, digoxin, clarithromycin, and rifampin.
Certain drug interactions with Viibryd can increase the risk of bleeding, dizziness, sleepiness, serotonin syndrome, or make Viibryd less effective. Serotonin syndrome, a potentially life-threatening condition caused by excessive serotonergic activity, can lead to symptoms such as nausea and vomiting, hallucinations, and changes in blood pressure.
If you have questions about alcohol and Viibryd, or drug interactions that may affect you, it's essential to ask your doctor or pharmacist for advice. It's especially important to avoid consuming alcohol while taking Viibryd, as alcohol can worsen certain side effects of the drug.
Before you start treatment with Viibryd, it's crucial to inform your doctor and pharmacist about any prescription, over-the-counter, and other medications you take. This includes specific examples of MAOIs like phenelzine, tranylcypromine, isocarboxazid, selegiline, linezolid, and moclobemide. These MAOIs should not be taken concurrently with Viibryd or within 14 days of stopping an MAOI due to the risk of serious interactions such as serotonin syndrome.
In addition to medications, certain medical conditions and other factors may increase the risk of interactions with Viibryd. These factors include being younger than age 24 years, narrow eye angles, low sodium levels, seizures, bleeding problems, mental health conditions, pregnancy, breastfeeding, allergic reaction, and other factors affecting health.
It's not known whether Viibryd is safe to take while pregnant or breastfeeding. If you are pregnant or breastfeeding, discuss the risks and benefits of taking Viibryd with your doctor.
While there are no specific reports of vitamins interacting with Viibryd, interactions with vitamins could be recognized in the future. Sharing information about supplements, herbs, and vitamins with your doctor and pharmacist before starting treatment with Viibryd may help prevent possible interactions.
Cannabis and cannabis products have been specifically reported to interact with Viibryd, potentially increasing the risk of side effects. No lab tests have been reported to interact with Viibryd, and vaccines have not been reported to interact with Viibryd either.
If you or someone you know is in crisis and considering suicide or self-harm, seek support from the 988 Lifeline, Crisis Text Line, Befrienders Worldwide, or local emergency services.
In summary, it's essential to be aware of potential drug interactions when taking Viibryd for major depressive disorder. Phenelzine, tranylcypromine, isocarboxazid, selegiline, linezolid, and moclobemide are notable MAOIs that can interact dangerously with Viibryd and must be avoided concomitantly. Always consult with your doctor or pharmacist for advice regarding drug interactions, and never stop taking a medication without discussing it with your healthcare provider first.
[1] DrugBank Online: https://go.drugbank.com/drugs/DB11752 [2] Mayo Clinic: https://www.mayoclinic.org/drugs-supplements/vilazodone-oral-route/precautions/drg-20073981 [3] FDA: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022496s029lbl.pdf [4] MedlinePlus: https://medlineplus.gov/druginfo/meds/a601215.html
- The science behind mental health and the prescribed drug Viibryd shows it can interact dangerously with certain monoamine oxidase inhibitors (MAOIs) like phenelzine, tranylcypromine, isocarboxazid, selegiline, linezolid, and moclobemide.
- Health-and-wellness advice includes informing your doctor and pharmacist about all medications you take, including these specific MAOIs, to ensure safe and effective treatment for major depressive disorder.
- Mental health professionals recommend consulting with a doctor or pharmacist regarding potential drug interactions, such as those between Viibryd and MAOIs, to avoid the risk of serotonin syndrome or medication ineffectiveness.
- In the health-and-wellness community, it is crucial to be aware that cannabis and cannabis products have been reported to interact with Viibryd and potentially increase the risk of side effects.
